A bit of a parallel between this and the last shot of Doc Ock at the end of Spider-Man 2.
Amazing Spider-Man (Vol. 1) #3
Published: c. May, 1963?
Cover Date: July, 1963
“Spider-Man Versus Doctor Octopus”
Writer: Stan Lee
Artist: Steve Ditko
Inker: Steve Ditko
Letterer: John Duffy
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It’s the debut of Beetle’s sleek new costume! Peter Parker, the Spectacular Spider-Man (Vol. 1) #58 Published: c. June, 1981? Cover Date: September, 1981 “Ring Out the Old, Ring in the New!” Writer: Roger Stern […]
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on Panel of the Day #1612 (Splash Page Sunday!): “I guess there was something different about Cindy Moon’s body chemistry, too.” Nov 11, 08:15
on Panel of the Day #1612 (Splash Page Sunday!): “I don’t like the whole “something was different with Peter’s body chemistry” explanation here. He was bitten by a spider…” Nov 11, 04:30
on 1994 Spider-Man #15: “Battle of the Insidious Six” Review: “Your complaints look like nitpicks and made-up. Why angry face should be indicative of seeing stone crushed?” Nov 10, 14:28 on Panel of the Day #1611: “I might be in the minority, but I’ve always been confused about Spider-man Noir’s wielding a gun.” Nov 8, 09:36 on Craig’s Critique: Amazing Spider-Man #60 (Legacy #954): “Hit The Road, Zeb” or “All [REDACTED] Things Must Come To An End”: “@Paul Penna: I just don’t see any future writer “doing” anything with Paul besides having him around. Marvel wants him…” Nov 6, 09:19 on Panel(s) of the Day #1610 (Mary Jane Monday!): “@Hornacek — I would make a horrible Spider-man. So many times, were I in his place, I would have confided…” Nov 5, 07:53 on Panel(s) of the Day #1610 (Mary Jane Monday!): “At least he said “I have to go take photos for the Bugle.” This is a valid excuse since this…” Nov 5, 04:26
on Craig’s Critique: Amazing Spider-Man #60 (Legacy #954): “Hit The Road, Zeb” or “All [REDACTED] Things Must Come To An End”: “Yep, as I predicted, Paul is here to stay. Marvel want Peter and MJ apart, and Paul is the story…” Nov 4, 17:43 on Panel(s) of the Day #1610 (Mary Jane Monday!): “Wow, Peter actually said, “I done blame her.”” Nov 4, 13:28 on Panel of the Day #1609 (Splash Page Sunday!): “Who knew Peter had a skirt in his closet made out of webbing?” Nov 4, 07:43
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Poor Otto. He’s been critically injured here, and his rescuers are calling him “Doctor Octopus” which at this point is an insult by his co-workers.
@William: No doubt. I hope it was.
Considering that Raimi is a massive fan of the Lee/Ditko comics and he probably went back to Ock’s first appearance for some inspiration, I wouldn’t be surprised if that was an intentional homage.