I assume Flash is talking about caffeinated beverages and not controlled substances.
Amazing Spider-Man (Vol. 1) #126
Published: c. August, 1973?
Cover Date: November, 1973
“The Kangaroo Bounces Back!”
Writer: Gerry Conway
Artist: Ross Andru
Inker: Jim Mooney
Letterer: Artie Simek
Colorist: Linda Lessmann
Gwen just died 4 issues ago, but good on Flash and MJ trying to get Peter to socialize to take his mind off of it.
Ah, so this is where Aunt May’s addiction began.