I would definitely get out of there as fast as possible if I were them.
Amazing Spider-Man (Vol. 1) #6
Published: c. September, 1963?
Cover Date: November, 1963
“Face-to-Face With… The Lizard!”
Writer: Stan Lee
Artist: Steve Ditko
Inker: Steve Ditko
Letterer: Artie Simek
I kind of prefer this evil scheming Lizard persona to the snarling beast writers often make him.