I'd say that if a run is ~100 issues then I would hope to remember at least a dozen memorable storylines - either single-issue or multi-part. I could use runs by Conway, JMS, JMD, etc to compare instead. As I said, there's nothing wrong with Micheline's run, it's just "there".
I re-read the run a couple years ago, and I can probably think of at least 10 memorable Michelinie single issue or multi-part stories:
1 - ASM #300 of course
2 - #308 - 310 / Mary Jane kidnapped, Styx & Stone, Spidey fights Taskmaster
3 - Return Of Venom, #317 - 318
4 - Cosmic Spidey kicks the shit out of Grey Hulk, #329
5 - Return Of Sinister Six; for ten year old me over one summer, this was a blast to read. ASM #334 -339. Otto was a coldhearted badass here, which is how he works best IMO.
6 - Powerless. Love this story. #341 -343
7 - #346 -347 - Venom vs Spidey on the deserted island. Would've been a good place to have left Brock.
8 - #361 -363 - Carnage's first, and best appearance.
9 - #365 Actually solid anniversary issue, Lizard
10 - #375 - Spidey fighting Venom again in the midst of the returned parents stuff boasts some phenomenal Bagley art, and introduced Ann Weying, Brock's ex-wife.
Sure there was lots of bad stuff in between a lot of these issues, even boring stuff, but it was very classically Amazing Spider-Man.
I can see how Slott can get to compared to him, but Michelinie is a much better writer overall than Slott.
hornacek wrote:Venom's appearance in #300 wasn't as momentous as ASM #200, #400, Spec #200, even Spec #100. They created a brand new villain we'd never heard of before (technically we hadn't, even though we knew about the symbiote) and who only appeared in the final page of the previous issue (minor appearances in ASM #298 and Web notwithstanding). And his legacy was almost immediately tarnished with his subsequent appearances, "brains brains!", Lethal Protector, etc.
And "most popular" doesn't automatically mean "best". To build upon my popcorn movie analogy about Micheline's run, Independence Day was the biggest grossing film of 1996. It's a great popcorn film, but it was nowhere near the best film of that year.
#300 was momentous in that, for better or worse, it signaled the start of a true new era for Spider-Man in a big way.
And it's not just that Venom is the last best villain because he's the most popular, but a lot of writers got a lot of mileage out him and the concept. He really is like the broken mirror image of Spidey, mixed with HR Giger. For some, that's an irresistible very-comic book concept.